9,10-Dihydro-9,10-methanoanthracene-9-carboxaldehyde → 9,10-Dihydro-9,10-methano-9-anthracenecarboxylic acid

HRID 27957ノート

反応式

HRID 27957 の反応式
[CH:1]([C:3]12[CH2:17][CH:10]([C:11]3[CH:12]=[CH:13][CH:14]=[CH:15][C:16]=31)[C:9]1[C:4]2=[CH:5][CH:6]=[CH:7][CH:8]=1)=[O:2].CC(C)=[O:20].OS(O)(=O)=O.O=[Cr](=O)=O>CC(C)=O.O>[CH:5]1[C:4]2[C:3]3([C:1]([OH:20])=[O:2])[CH2:17][CH:10]([C:11]4[C:16]3=[CH:15][CH:14]=[CH:13][CH:12]=4)[C:9]=2[CH:8]=[CH:7][CH:6]=1

参加物

5

反応物 2

HCID 124041419,10-Dihydro-9,10-methanoanthracene-9-carboxaldehydeHCID 131709961Jones' reagent

生成物 1

HCID 125071199,10-Dihydro-9,10-methano-9-anthracenecarboxylic acid

試薬・触媒・溶媒 2

HCID 180Acetone溶媒HCID 962Water溶媒

実験手順

To a solution of 9-formyl-9,10-dihydro-9,10-methanoanthracene (3.5 g) in acetone (17 ml) was dropwise added Jones' reagent (5.0 ml) at room temperature. The reaction mixture was stirred at room temperature for 1 hour, diluted with water and extracted with ethyl acetate. The ethyl acetate extract was washed with water, dried over anhydrous sodium sulfate and evaporated to dryness to give 9,10-dihydro-9,10-methanoanthracene-9-carboxylic acid. M.P. 199.5°-200.5° C.

後処理

  1. customat room temperature
  2. extractionextracted with ethyl acetate
  3. extractionThe ethyl acetate extract
  4. washwas washed with water
  5. dry with materialdried over anhydrous sodium sulfate
  6. customevaporated to dryness

出典と根拠

ORDレコード
ord-d3683597ab7d47bfbec6414f5d435c33
出典データセット
uspto-grants-1980_09
特許番号
US04224344

反応ノート

読み込み中…