HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Chloropyridine → 3-(N-methyl-N-(4-pyridyl)amino)propanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Chloropyridine | HCID 12288 | — |
| Reactant | 3-(Methylamino)-1-propanol | HCID 10148986 | — |
| Product | 3-(N-methyl-N-(4-pyridyl)amino)propanol | HCID 22625038 | 2,560.8% |
Reaction Steps
Using a procedure analogous to that described for the starting material in Example 46, 4-chloropyridine (885 mg, 59 mmol) and 3-(methylamino)propanol (2.1 g, 0.23 mmol), (Tetrahedron Lett. 1994, 35, 1545-1548), were heated for 8 hours to give 3-(N-methyl-N-(4-pyridyl)amino)propanol (979 mg, 61%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06362336B1 |
| Source dataset | uspto-grants-2002_03 |
| ORD ID | ord-ad9e9ab02d9249ee8a8296d145b7db35 |
| Source note | uspto-grants-2002_03 |