化工社化工社 化学情報印刷レポート · 研究参考用
HCID 22624891、化合物 → 2-(Pyridin-3-yloxy)ethan-1-ol
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | HCID 22624891 | HCID 22624891 | — |
| 溶媒 | Acetic Acid | HCID 176 | — |
| 溶媒 | Water | HCID 962 | — |
| 溶媒 | Tetrahydrofuran | HCID 8028 | — |
| 生成物 | 2-(Pyridin-3-yloxy)ethan-1-ol | HCID 21908997 | 86% |
反応手順
A solution of 3-(2-(tetrahydropyran-2-yloxy)ethoxy)pyridine (1.54 g, 7 mmol) in acetic acid (8 ml), THF (4 ml) and water (2 ml) was heated at 50° C. for 4 hours. The volatiles were removed by evaporation and the residue azeotroped with toluene to give 3-(2-hydroxyethoxy)pyridine (820 mg, 86%) as an off-white solid.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06362336B1 |
| 出典データセット | uspto-grants-2002_03 |
| ORD ID | ord-27d37db75bc147aaac8aa4d41bb8802f |
| 出典メモ | uspto-grants-2002_03 |