O-Benzylhydroxylamine → HCID 53919629, compound

HRID 279713Notes

Reaction equation

HRID 279713 reaction equation
[C:1]1([CH3:29])[CH:6]=[CH:5][C:4]([S:7]([N:10]2[CH2:28][CH2:27][CH2:26][C@H:11]2[C:12]([NH:14][C@H:15]([C:23]([OH:25])=O)[CH2:16][C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)=[O:13])(=[O:9])=[O:8])=[CH:3][CH:2]=1.[CH2:30]([O:37][NH2:38])[C:31]1[CH:36]=[CH:35][CH:34]=[CH:33][CH:32]=1>>[CH2:30]([O:37][NH:38][C:23](=[O:25])[C@H:15]([CH2:16][C:17]1[CH:18]=[CH:19][CH:20]=[CH:21][CH:22]=1)[NH:14][C:12](=[O:13])[C@@H:11]1[CH2:26][CH2:27][CH2:28][N:10]1[S:7]([C:4]1[CH:3]=[CH:2][C:1]([CH3:29])=[CH:6][CH:5]=1)(=[O:9])=[O:8])[C:31]1[CH:36]=[CH:35][CH:34]=[CH:33][CH:32]=1

Participants

3

Reactant 2

HCID 102313O-BenzylhydroxylamineHCID 9931728HCID 9931728, compound

Product 1

HCID 53919629HCID 53919629, compound

Procedure

N-(Toluene-4-sulfonyl)-L-prolyl-L-phenylalanine was coupled to O-benzylhydroxylamine using the procedure described in Method 3 to give the title compound as a white solid, mp=127-130° C.

Sources & evidence

ORD record
ord-9b2ff1983dda43baa95fa2535b59f7b7
Source dataset
uspto-grants-2002_03
Patent number
US06362341B1

Reaction notes

Loading…