Acetic Anhydride → HCID 13131731, compound

Participants

Reaction Steps

1.9 g of 17-benzoyloxy-11β,21-dihydroxy-6α-methyl-1,4-pregnadiene-3,20-dione is reacted, analogously to Example 2c, with acetic anhydride and worked up. The crude product is purified on 200 g of silica gel with a methylene chloride-acetone gradient (0-12% acetone), thus isolating 1.8 g of 21-acetoxy-17-benzoyloxy-11β-hydroxy-6α-methyl-1,4-pregnadiene-3,20-dione, mp 258° C.

Provenance & Evidence