Methyl carbazate → HCID 57214088, compound

HRID 279882Notes

Reaction equation

HRID 279882 reaction equation
[C:1]1([CH:7]=[C:8]2[CH2:13][CH2:12][CH2:11][CH2:10][C:9]2=O)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH3:15][O:16][C:17]([NH:19][NH2:20])=[O:18]>C(O)C>[CH3:15][O:16][C:17]([NH:19][N:20]=[C:9]1[CH2:10][CH2:11][CH2:12][CH2:13][C:8]1=[CH:7][C:1]1[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1)=[O:18]

Participants

4

Reactant 2

HCID 80519Methyl carbazateHCID 989262-Benzylidenecyclohexanone

Product 1

HCID 57214088HCID 57214088, compoundYield 98%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent2×

Procedure

To a solution of 37.2 g (0.2 moles) of 2-phenylmethylenecyclohexan-1-one in 200 ml of anhydrous ethanol a solution of 18.0 g (0.2 moles) of N-methoxycarbonyl hydrazine in 40 ml of anhydrous ethanol is added, under stirring. The reaction mixture is boiled for a short while, then cooled, clarified with activated carbon, filtered and the filtrate is cooled. The separated white crystals are filtered off and dried. 50.63 g of the desired compound are obtained. Yield: 98%.

Workup

  1. temperaturecooled
  2. filtrationfiltered
  3. temperaturethe filtrate is cooled
  4. filtrationThe separated white crystals are filtered off
  5. customdried

Sources & evidence

ORD record
ord-df136fd670764adfafe3ec78e5d2cb7c
Source dataset
uspto-grants-1986_05
Patent number
US04587261

Reaction notes

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