2-Phenylmethylenecyclopentanone → HCID 57104997, compound

HRID 279888Notes

Reaction equation

HRID 279888 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:10]=[C:11]([O:16][CH3:17])[C:12]=1[O:13][CH2:14][CH3:15])[C:6]([NH:8][NH2:9])=[O:7].[C:18]1([CH:24]=[C:25]2[CH2:29][CH2:28][CH2:27][C:26]2=O)[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1>C(O)C>[CH3:17][O:16][C:11]1[CH:10]=[C:5]([CH:4]=[C:3]([O:2][CH3:1])[C:12]=1[O:13][CH2:14][CH3:15])[C:6]([NH:8][N:9]=[C:26]1[CH2:27][CH2:28][CH2:29][C:25]1=[CH:24][C:18]1[CH:19]=[CH:20][CH:21]=[CH:22][CH:23]=1)=[O:7]

Participants

4

Reactant 2

HCID 2668132-PhenylmethylenecyclopentanoneHCID 126543144-Ethoxy-3,5-dimethoxybenzohydrazide

Product 1

HCID 57104997HCID 57104997, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent2×

Procedure

A solution of 30.2 g (0.126 moles) of 3,5-dimethoxy-4-ethoxybenzoic acid hydrazide in 250 cm3 of anhydrous ethanol is added to a solution of 21.8 g (0.126 moles) of 2-phenylmethylenecyclopentan-1-one in 50 cm3 of ethanol. The reaction mixture is boiled for one hour, then cooled. The separated crystals are filtered off and dried. Yield: 39.78 g (80.0%). M.p.: 239°-240° C.

Workup

  1. temperaturecooled
  2. filtrationThe separated crystals are filtered off
  3. customdried

Sources & evidence

ORD record
ord-2cf707fb4871448db5575b150df759cc
Source dataset
uspto-grants-1986_05
Patent number
US04587261

Reaction notes

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