N-methoxy-N-methyl-2,4-dimethyl-5-oxazolecarboxamide → t-Butyl 2,4-Dimethyl-5-oxazolyl Ketone

HRID 2799Notes

Reaction equation

HRID 2799 reaction equation
CON(C)[C:4]([C:6]1[O:10][C:9]([CH3:11])=[N:8][C:7]=1[CH3:12])=[O:5].[C:14]([Li])([CH3:17])([CH3:16])[CH3:15]>>[CH3:11][C:9]1[O:10][C:6]([C:4]([C:14]([CH3:17])([CH3:16])[CH3:15])=[O:5])=[C:7]([CH3:12])[N:8]=1

Participants

3

Reactant 2

HCID 18936346N-methoxy-N-methyl-2,4-dimethyl-5-oxazolecarboxamideHCID 178418306HCID 178418306, compound

Product 1

HCID 18936339t-Butyl 2,4-Dimethyl-5-oxazolyl Ketone

Procedure

Starting with N-methoxy-N-methyl-2,4-dimethyl-5-oxazolecarboxamide and t-butyllithium and following the general method of Preparation 3, the title compound was prepared.

Workup

  1. customthe general method of Preparation 3

Sources & evidence

ORD record
ord-24c2c46a829e48159acfde789ed8bd92
Source dataset
uspto-grants-1998_03
Patent number
US05731335

Reaction notes

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