HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl iodide → 7-Methoxy-4-methyl-4H-benzo[1,4]oxazin-3-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl iodide | HCID 6328 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 7-Methoxy-2H-1,4-benzoxazin-3(4H)-one | HCID 11600770 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | 7-Methoxy-4-methyl-4H-benzo[1,4]oxazin-3-one | HCID 23323013 | 92% |
Reaction Steps
Following the procedure of Example 1, 21.7 g of 3-oxo-7-methoxy-3,4-dihydro-2H-[1,4]benzoxazine and 19.88 g of methyl iodide were reacted in 600 ml of acetone in the presence of 19.32 g of solid potassium carbonate. The reaction was carried out, and the product isolated and purified by the procedure of Example 1 to yield 3-oxo-4-methyl-7-methoxy-3,4-dihydro-2H-[1,4]benzoxazine; yield=92%; molecular ion by mass spectrum=193.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04587336 |
| Source dataset | uspto-grants-1986_05 |
| ORD ID | ord-ff92bffa867c41b3a5582dbc3d2f30b7 |
| Source note | uspto-grants-1986_05 |