Hydrochloric Acid → HCID 53664003, compound

Participants

Reaction Steps

A 10 g quantity of piperidinium N-(3-hydroxy-4-methoxycinnamoyl)anthranilate is dissolved in a mixture of 80 ml of water and 80 ml of methyl alcohol with heating, and the resultant solution is added dropwise to 85 ml of diluted hydrochloric acid (5 ml of conc. hydrochloric acid and 80 ml of water) with stirring. The precipitated crystals which form are collected by filtration, washed with water and then dried at 90°-100° C. under reduced pressure for 3 hours to yield N-(3-hydroxy-4-methoxycinnamoyl)anthranilic acid (97.0% yield), m.p. 219°-222° C. The compound structure is confirmed by elemental analysis, and by IR and NMR spectroscopy.

Provenance & Evidence