HCID 13645987, compound → HCID 13645989, compound

Participants

Reaction Steps

Under nitrogen a solution of N-(1,1-dimethylethyl)-2-(methylselenyl)benzenesulfonamide (34.5 g, 0.113 mmol) in trifluoroacetic acid (100 mL) was stirred at room temperature overnight. The solvent was then rotary evaporated to leave an amber solid. This was again treated with trifluoroacetic acid (100 mL) at room temperature overnight. The mixture was concentrated in vacuo, then poured into ice-water. The solid was collected, rinsed with ice-water, and dried in vacuo. The crude product was recrystallized from hot benzene (5 mL/g), collected at room temperature, rinsed with benzene and hexanes, and dried. The 2-(methylselenyl)benzenesulfonamide (23.1 g) obtained melted at 119°-121° C.

Provenance & Evidence