Dichloromethane → HCID 54436487, compound

Participants

Reaction Steps

Pyridinium dichromate (9.24 g, 1.8 equivalents) was added to a methylene chloride solution of the benzyl alcohol product of step (q), above, at room temperature. The reaction was stirred for 24 hours, then diluted with diethyl ether and filtered. The filtrate was concentrated on a rotary evaporator and the residual oil was taken up in MTBE and washed with 2N hydrochloric acid, aqueous NaHCO3, brine, treated with charcoal, dried and concentrated on a rotary evaporator to give the product of this step as a pale yellow oil. The product was distilled under reduced pressure (~0.5 mm Hg) using a Kugelrohr apparatus to give 3.3 g of refined product as a clear oil.

Provenance & Evidence