HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 280098Generated: October 30, 2026
Dimethylformamide → HCID 13389312, compound
https://huagongshe.com/reaction/280098
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | Phosphorus oxychloride | HCID 24813 | — |
| Reactant | HCID 13389311 | HCID 13389311 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 13389312 | HCID 13389312 | — |
Reaction Steps
2.3 ml (0.025 mol) of phosphorus oxychloride are added dropwise to 20 ml of dimethylformamide at 0°-5° C. 5.7 g (0.02 mol) of 2-diethylaminomethyl-6-phenyl-imidazo-[2,1-b]-1,3,4-thiadiazole are then added and the mixture is warmed at 100° C. for 2 hours. After cooling, 50 ml of water are added and the mixture is neutralised with 20% strength sodium hydroxide solution and extracted with ether.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US04588723 |
|---|
| Source dataset | uspto-grants-1986_05 |
|---|
| ORD ID | ord-d929749fa4b24bd6ae4b21988338c90b |
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| Source note | uspto-grants-1986_05 |
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