HCID 20138883, compound → HCID 13756027, compound

HRID 280172Notes

Reaction equation

HRID 280172 reaction equation
[CH3:1][O:2][C:3]1[CH:12]=[CH:11][CH:10]=[C:9]2[C:4]=1[CH:5]=[CH:6][CH2:7][CH:8]2[CH2:13][N:14]1[CH2:19][CH2:18][CH2:17][CH2:16][CH2:15]1>[Pd].C(O)C>[CH3:1][O:2][C:3]1[CH:12]=[CH:11][CH:10]=[C:9]2[C:4]=1[CH2:5][CH2:6][CH2:7][CH:8]2[CH2:13][N:14]1[CH2:19][CH2:18][CH2:17][CH2:16][CH2:15]1

Participants

4

Reactant 1

HCID 20138883HCID 20138883, compound

Product 1

HCID 13756027HCID 13756027, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

5% Palladium on carbon (3.0 g) is added to a solution of 5-methoxy-1-piperidinylmethyl-1,2-dihydronaphthalene (63 g) in absolute ethanol (600 ml) and placed under H2 at an initial pressure of 47 psi for 30 min. The reaction mixture is filtered and the filtrate evaporated in vacuo yielding the desired product as an oil.

Workup

  1. customfor 30 min
  2. filtrationThe reaction mixture is filtered
  3. customthe filtrate evaporated in vacuo

Sources & evidence

ORD record
ord-824b5ed136fe4202862feda7f3922de6
Source dataset
uspto-grants-1986_05
Patent number
US04588719

Reaction notes

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