HCID 54206619, compound → HCID 20138914, compound

HRID 280181Notes

Reaction equation

HRID 280181 reaction equation
[C:1]([CH:3]=[C:4]([C:6]1[CH:11]=[CH:10][C:9]([O:12][CH3:13])=[CH:8][CH:7]=1)[CH3:5])#[N:2]>[Pd].C(O)C>[C:1]([CH2:3][CH:4]([C:6]1[CH:7]=[CH:8][C:9]([O:12][CH3:13])=[CH:10][CH:11]=1)[CH3:5])#[N:2]

Participants

4

Reactant 1

HCID 54206619HCID 54206619, compound

Product 1

HCID 20138914HCID 20138914, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

A suspension of the 1-cyano compound of Step 1. (53.2 g) and 5% palladium on carbon (5.3 g) in ethanol (530 ml) is stirred under an atmosphere of H2 for four hours. The reaction mixture is filtered, and the filtrate evaporated in vacuo affording the crude product as an oil.

Workup

  1. filtrationThe reaction mixture is filtered
  2. customthe filtrate evaporated in vacuo

Sources & evidence

ORD record
ord-0400f660725a47a3ae5c73be8386d0d7
Source dataset
uspto-grants-1986_05
Patent number
US04588719

Reaction notes

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