HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-(p-Hydroxymethylphenyl)imidazo[1,5-a]pyridine → 5-(p-Formylphenyl)-imidazo[1,5-a]pyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-(p-Hydroxymethylphenyl)imidazo[1,5-a]pyridine | HCID 13649432 | — |
| Catalyst | HCID 178418406 | HCID 178418406 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 5-(p-Formylphenyl)-imidazo[1,5-a]pyridine | HCID 13649433 | — |
Reaction Steps
A solution of 5-(p-hydroxymethylphenyl)imidazo[1,5-a]pyridine (0.52 g) in 10 ml of methylene chloride is refluxed with 5.2 g of activated manganese dioxide for 24 hours. An additional 5.2 g of manganese dioxide is added and the reaction mixture is refluxed an additional 6 hours, filtered, and the solvent is evaporated to yield 5-(p-formylphenyl)-imidazo[1,5-a]pyridine, m.p. 144°-146°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04588732 |
| Source dataset | uspto-grants-1986_05 |
| ORD ID | ord-de6a9596e4b34d389962253cfde21811 |
| Source note | uspto-grants-1986_05 |