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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 280222Generated: October 29, 2026

Sulfuric Acid → Imidazo(1,5-a)pyridine

https://huagongshe.com/reaction/280222

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSulfuric AcidHCID 1118—
ReactantHCID 23321853HCID 23321853—
SolventSodium HydroxideHCID 14798—
ProductImidazo(1,5-a)pyridineHCID 274090—

Reaction Steps

A solution of 5-[p-(cyanomethyl)phenethyl]imidazo[1,5-a]pyridine (1.0 g) in 2N sodium hydroxide (30 ml) is heated under reflux for 15 hours, acidified with concentrated sulfuric acid and filtered to yield 5-[p-carboxymethyl)phenethyl]imidazo[1,5-a]pyridine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04588732
Source datasetuspto-grants-1986_05
ORD IDord-5bf1005df9534729a900856b94de56d3
Source noteuspto-grants-1986_05