HCID 23321861, compound → HCID 23321866, compound

HRID 280223Notes

Reaction equation

HRID 280223 reaction equation
[OH:1][CH2:2][C:3]1[CH:19]=[CH:18][C:6]([CH2:7][CH2:8][C:9]2[N:14]3[CH:15]=[N:16][CH:17]=[C:13]3[CH:12]=[CH:11][CH:10]=2)=[CH:5][CH:4]=1>C(Cl)Cl.[O-2].[O-2].[Mn+4]>[CH:2]([C:3]1[CH:4]=[CH:5][C:6]([CH2:7][CH2:8][C:9]2[N:14]3[CH:15]=[N:16][CH:17]=[C:13]3[CH:12]=[CH:11][CH:10]=2)=[CH:18][CH:19]=1)=[O:1]

Participants

4

Reactant 1

HCID 23321861HCID 23321861, compound

Product 1

HCID 23321866HCID 23321866, compound

Reagents, catalysts & solvents 2

HCID 178418406HCID 178418406, compoundCatalystHCID 6344DichloromethaneSolvent

Procedure

5-[p-(Hydroxymethyl)phenethyl]imidazo[1,5-a]pyridine (2.52 g) is refluxed in 100 ml of methylene chloride with 25.2 g of activated manganese dioxide for 24 hours. The mixture is filtered and evaporated to yield 5-(p-formylphenethyl)imidazo[1,5-a]pyridine.

Workup

  1. filtrationThe mixture is filtered
  2. customevaporated

Sources & evidence

ORD record
ord-0e1b2afa5c00412ea7a4a5d8e2ce0756
Source dataset
uspto-grants-1986_05
Patent number
US04588732

Reaction notes

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