HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 23321888, compound → HCID 13649435, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 23321888 | HCID 23321888 | — |
| Solvent | Ethanol | HCID 702 | — |
| Solvent | Sodium Hydroxide | HCID 14798 | — |
| Product | HCID 13649435 | HCID 13649435 | — |
Reaction Steps
5-[4-(Ethoxycarbonylmethylthio)butyl]imidazo[1,5-a]pyridine (4.4 g) in 30 ml of ethanol and 61 ml of 1.0N sodium hydroxide is heated under reflux for 3 hours. The ethanol is evaporated, the aqueous is extracted with ethyl acetate (20 ml) and the pH adjusted to 5. The resulting oil is crystallized from ethanol to yield 5-[4-(carboxymethylthio)butyl]imidazo[1,5-a]pyridine, m.p. 124°-126°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04588732 |
| Source dataset | uspto-grants-1986_05 |
| ORD ID | ord-ad7cf82c9b2144cabc2bd3a0c43df66c |
| Source note | uspto-grants-1986_05 |