HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → 5-(Chloromethyl)imidazo[1,5-a]pyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | Sodium borohydride | HCID 4311764 | — |
| Reactant | Imidazo(1,5-a)pyridine-5-carbaldehyde | HCID 13206163 | — |
| Reactant | Imidazo[1,5-a]pyridin-5-ylmethanol | HCID 23321868 | — |
| Product | 5-(Chloromethyl)imidazo[1,5-a]pyridine | HCID 23321855 | — |
Reaction Steps
5-Chloromethylimidazo[1,5-a]pyridine is prepared from 5-formylimidazo-[1,5-a]pyridine by reduction with sodium borohydride to 5-hydroxymethylimidazo[1,5-a]pyridine and subsequent treatment with thionyl chloride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04588732 |
| Source dataset | uspto-grants-1986_05 |
| ORD ID | ord-b350f305caaf474c99183e1491f8b558 |
| Source note | uspto-grants-1986_05 |