HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → Imidazo(1,5-a)pyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 5-[2-(p-[Ethoxycarbonylmethoxy]phenyl)ethen-1-yl]imidazo[1,5-a]pyridine | HCID 53874958 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | Imidazo(1,5-a)pyridine | HCID 274090 | — |
Reaction Steps
5-[2-(p-[Ethoxycarbonylmethoxy]phenyl)-ethen-1-yl]imidazo[1,5-a]pyridine (3.2 g) is refluxed in 30 ml of ethanol with 20 ml of 1N sodium hydroxide for 3 hours. The ethanol is evaporated and the aqueous phase is adjusted to pH=6. Filtration yields the substituted phenoxyacetic acid 5-[2-(p-carboxymethoxy]phenyl)ethen-1-yl]imidazo[1,5-a]pyridine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04588732 |
| Source dataset | uspto-grants-1986_05 |
| ORD ID | ord-e0a7a2ada4714c109a156fdd55e28072 |
| Source note | uspto-grants-1986_05 |