HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Amino-1-(3-fluorophenyl)ethan-1-ol → HCID 23322168, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Amino-1-(3-fluorophenyl)ethan-1-ol | HCID 35800 | — |
| Reactant | Fumaric Acid | HCID 444972 | — |
| Reactant | 2-Amino-1-(3-chlorophenyl)ethan-1-ol | HCID 3751601 | — |
| Product | HCID 23322168 | HCID 23322168 | — |
Reaction Steps
The title compound was prepared in the manner described in Example 3 replacing 2-(3-chlorophenyl)-2-hydroxyethanamine with 2-(3-fluorophenyl)-2-hydroxyethanamine. The chromatographed material was treated with methanolic fumaric acid and the derived salt recrystallised from ethyl acetate to give the title compound (fumarate), mp 58-83, as a 52-48 mixture of diastereoisomers.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04588749 |
| Source dataset | uspto-grants-1986_05 |
| ORD ID | ord-cae322d37bd94ec9aae0e1baf9fe6a28 |
| Source note | uspto-grants-1986_05 |