Phenylethanolamine → HCID 23322164, compound

HRID 280319Notes

Reaction equation

HRID 280319 reaction equation
[OH:1][CH:2]([C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1)[CH2:3][NH2:4].[CH3:11][C:12]1[CH:17]=[C:16]([CH3:18])[CH:15]=[CH:14][C:13]=1[CH2:19][C:20](=O)[CH3:21]>>[CH3:11][C:12]1[CH:17]=[C:16]([CH3:18])[CH:15]=[CH:14][C:13]=1[CH2:19][CH:20]([NH:4][CH2:3][CH:2]([OH:1])[C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1)[CH3:21]

Participants

3

Reactant 2

HCID 1000PhenylethanolamineHCID 3564155HCID 3564155, compound

Product 1

HCID 23322164HCID 23322164, compound

Procedure

The title compound was reprepared as a 49:51 mixture of diastereoisomers m.p. 58-63 in the manner described in Example 3 using 2-hydroxy-2-phenylethanamine and (2,4-dimethylphenyl)propanone. 'Hnmr identical with that of Example 32.

Sources & evidence

ORD record
ord-0f2e7aad1337408eb207d8cf281f1ce8
Source dataset
uspto-grants-1986_05
Patent number
US04588749

Reaction notes

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