化工社化工社 化学情報印刷レポート · 研究参考用
Pyrazine → 1-(2-Pyrazinyl)-2,2-dimethylpropanone
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Pyrazine | HCID 9261 | — |
| 反応物 | Pivalaldehyde | HCID 12417 | — |
| 溶媒 | Dichloromethane | HCID 6344 | — |
| 生成物 | 1-(2-Pyrazinyl)-2,2-dimethylpropanone | HCID 546031 | 11% |
反応手順
The reaction of pyrazine and trimethylacetaldehyde is conducted in the manner described in Example I on the same molar scale. Preparative thick layer chromatography (2000μ silica gel GF, developed with methylene chloride) of the crude reaction product provides an 11% yield of 1-pyrazinyl-2,2-dimethyl-1-propanone.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04588813 |
| 出典データセット | uspto-grants-1986_05 |
| ORD ID | ord-78d20b627add4015a20ffd02abad92f2 |
| 出典メモ | uspto-grants-1986_05 |