HuagongsheHuagongshe Chemistry Print Report · For research reference only
Propanal → 1-(5,6-Dimethylpyrazin-2-yl)propan-1-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Propanal | HCID 527 | — |
| Reactant | 2,3-Dimethylpyrazine | HCID 22201 | — |
| Solvent | Acetone hexane | HCID 21880519 | — |
| Product | 1-(5,6-Dimethylpyrazin-2-yl)propan-1-one | HCID 572256 | 25% |
Reaction Steps
The reaction of 2,3-dimethylpyrazine and freshly distilled propionaldehyde is carried out as described in Example I on the same molar scale. Preparative thick layer chromatography (2000μ silica gel GF, developed in 5% acetone/hexane) of the crude reaction product gives a 25% yield of 1-(2,3-dimethyl-5-pyrazinyl)-1-propanone.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04588813 |
| Source dataset | uspto-grants-1986_05 |
| ORD ID | ord-27fa5aad926344578eebc7384e3397a6 |
| Source note | uspto-grants-1986_05 |