HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-Chloro-2-picoline → 3-({4-[(Piperidin-1-yl)methyl]pyridin-2-yl}oxy)propan-1-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-Chloro-2-picoline | HCID 87601 | — |
| Reactant | 2-Bromo-4-methylpyridine | HCID 2734087 | — |
| Reactant | 3-({6-[(Piperidin-1-yl)methyl]pyridin-2-yl}oxy)propan-1-amine | HCID 13491500 | — |
| Product | 3-({4-[(Piperidin-1-yl)methyl]pyridin-2-yl}oxy)propan-1-amine | HCID 14625102 | — |
Reaction Steps
When the general procedure for the preparation of 3-(6-piperidinomethyl-2-pyridyloxy)propylamine described in U.K. Patent Application No. 2,098,988 was followed except that the 2-chloro-6-methylpyridine utilized therein was replaced by 2-bromo-4-methylpyridine, then the title compound was produced as an oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04588826 |
| Source dataset | uspto-grants-1986_05 |
| ORD ID | ord-4ea47e4abea848b88897d89ea66d6759 |
| Source note | uspto-grants-1986_05 |