m,alpha-Dichlorotoluene → 2-[2'-(3"-Chlorobenzylthio)-5'-chlorophenyl]-imidazoline hydrochloride

HRID 280429Notes

Reaction equation

HRID 280429 reaction equation
[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[S:13][C:8]3([NH:12][CH2:11][CH2:10][NH:9]3)[C:6]=2[CH:7]=1.[Cl:14][C:15]1[CH:16]=[C:17]([CH:20]=[CH:21][CH:22]=1)[CH2:18]Cl>CO>[ClH:1].[Cl:14][C:15]1[CH:16]=[C:17]([CH:20]=[CH:21][CH:22]=1)[CH2:18][S:13][C:5]1[CH:4]=[CH:3][C:2]([Cl:1])=[CH:7][C:6]=1[C:8]1[NH:12][CH2:11][CH2:10][N:9]=1

Participants

4

Reactant 2

HCID 12103m,alpha-DichlorotolueneHCID 704691194-Chlorobenzothietane-2-spiro-2'-imidazoline

Product 1

HCID 704696352-[2'-(3"-Chlorobenzylthio)-5'-chlorophenyl]-imidazoline hydrochloride

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

32 Parts of 4-chlorobenzothietane-2-spiro-2'-imidazolidine is reacted with 26 parts of 3-chlorobenzyl chloride in 300 parts of methanol, as described in Example 11. The yield is 49 parts (85% of theory ) and the melting point is 255° C.

Sources & evidence

ORD record
ord-d9b87056ed6e4163915204f804ff3dbe
Source dataset
uspto-grants-1986_05
Patent number
USRE032154

Reaction notes

Loading…