2,4-Dichlorobenzyl chloride → 2-[2'-(2",4"-Dichlorobenzylthio)-5'-chlorophenyl]-imidazoline hydrochloride

HRID 280430Notes

Reaction equation

HRID 280430 reaction equation
[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[S:13][C:8]3([NH:12][CH2:11][CH2:10][NH:9]3)[C:6]=2[CH:7]=1.[Cl:14][C:15]1[CH:22]=[C:21]([Cl:23])[CH:20]=[CH:19][C:16]=1[CH2:17]Cl>CO>[ClH:1].[Cl:14][C:15]1[CH:22]=[C:21]([Cl:23])[CH:20]=[CH:19][C:16]=1[CH2:17][S:13][C:5]1[CH:4]=[CH:3][C:2]([Cl:1])=[CH:7][C:6]=1[C:8]1[NH:12][CH2:11][CH2:10][N:9]=1

Participants

4

Reactant 2

HCID 72122,4-Dichlorobenzyl chlorideHCID 704691194-Chlorobenzothietane-2-spiro-2'-imidazoline

Product 1

HCID 704696412-[2'-(2",4"-Dichlorobenzylthio)-5'-chlorophenyl]-imidazoline hydrochloride

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

32 Parts of 4-chlorobenzothietane-2-spiro-2'-imidazolidine is reacted in 300 parts of methanol with 29.5 parts of 2,4-dichlorobenzyl chloride in the manner described in Example 11. The yield is 56 parts (90% of theory) and the melting point is 236° C.

Sources & evidence

ORD record
ord-3f9b7d05831d4e099ac9e4a1eaba8d18
Source dataset
uspto-grants-1986_05
Patent number
USRE032154

Reaction notes

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