HuagongsheHuagongshe Chemistry Print Report · For research reference only
Toluene → N-{4-[(1,2-Benzothiazol-5-yl)oxy]phenyl}-N'-methylurea
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Toluene | HCID 1140 | — |
| Reactant | Methyl Isocyanate | HCID 12228 | — |
| Reactant | 4-[(1,2-Benzothiazol-5-yl)oxy]aniline | HCID 13269398 | — |
| Solvent | Triethylamine | HCID 8471 | — |
| Product | N-{4-[(1,2-Benzothiazol-5-yl)oxy]phenyl}-N'-methylurea | HCID 13269403 | 85% |
Reaction Steps
24.2 parts of 5-(4'-aminophenoxy)-benzisothiazole, 400 parts of toluene, 1 part of triethylamine and 11.4 parts of methyl isocyanate were heated at 80° C. for 12 hours, and the reaction mixture was then evaporated down under reduced pressure. 25 parts (85% of theory) of 5-(4'-methylaminocarbonylaminophenoxy)-benzisothiazole of melting point 178° C. were obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04589910 |
| Source dataset | uspto-grants-1986_05 |
| ORD ID | ord-5fe0223b8e87453fb76a6d3ed74252cd |
| Source note | uspto-grants-1986_05 |