HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 280434Generated: October 31, 2026
Dimethylamine → N'-{4-[(1,2-Benzothiazol-5-yl)oxy]phenyl}-N,N-dimethylurea
https://huagongshe.com/reaction/280434
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Dimethylamine | HCID 674 | — |
| Reactant | 5-(4-Isocyanatophenoxy)-1,2-benzothiazole | HCID 13269399 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | N'-{4-[(1,2-Benzothiazol-5-yl)oxy]phenyl}-N,N-dimethylurea | HCID 13269404 | 88% |
Reaction Steps
5 parts of gaseous dimethylamine were passed into a solution of 26.8 parts of 5-(4'-isocyanatophenoxy)-benzisothiazole in 300 parts of diethyl ether, the reaction mixture was stirred for 12 hours at from 20 to 30° C., and the resulting precipitate was isolated. 27.6 parts (88% of theory) of 5-(4'-dimethylaminocarbonylaminophenoxy)-benzisothiazole of melting point 156° C. were obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US04589910 |
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| Source dataset | uspto-grants-1986_05 |
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| ORD ID | ord-6979be0fe24f4b6087dd4b1227e56ead |
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| Source note | uspto-grants-1986_05 |
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