Diethyl Ether → HCID 53897982, compound

Participants

Reaction Steps

A solution of 6.1 parts of N-methoxy-N-methylamine in 100 parts of diethyl ether was added to a solution of 30.3 parts of 5-(2'-chloro-4'-isocyanatophenoxy)-benzisothiazole in 300 parts of diethyl ether at from 20° to 30° C., and after 12 hours at this temperature the reaction mixture was evaporated down and the residue was treated with about 50 parts of diethyl ether. 30.2 parts (83% of theory) of 5-[2'-chloro-4'-(N-methoxy-N-methylaminocarbonylamino)-phenoxy]-benzisothiazole of melting point 128° C. were obtained.

Provenance & Evidence