Pyrrolidone carboxylic acid → HCID 23320543, compound

HRID 280493Notes

Reaction equation

HRID 280493 reaction equation
[NH:1]1[CH:5]([C:6]([OH:8])=O)[CH2:4][CH2:3][C:2]1=[O:9].[CH3:10][N:11]([CH2:13][CH2:14][CH2:15][NH2:16])[CH3:12]>>[CH3:10][N:11]([CH3:12])[CH2:13][CH2:14][CH2:15][NH:16][C:6]([CH:5]1[CH2:4][CH2:3][C:2](=[O:9])[NH:1]1)=[O:8]

Participants

3

Reactant 2

HCID 499Pyrrolidone carboxylic acidHCID 7993N,N-Dimethyl-1,3-propanediamine

Product 1

HCID 23320543HCID 23320543, compound

Conditions

Temperature
165 °C

Procedure

129 Grams of 2-pyrrolidone-5-carboxylic acid were slowly added to 133 g of dimethylaminopropylamine with mixing. This mixture was then stirred and heated for 8-10 hours at 165° C. The excess amine was then distilled off leaving the title product in the form of an amber colored watersoluble solid.

Workup

  1. additionwith mixing
  2. distillationThe excess amine was then distilled off

Sources & evidence

ORD record
ord-0f39a4279b2d4a23b0dd21cb690cfe86
Source dataset
uspto-grants-1986_05
Patent number
US04590069

Reaction notes

Loading…