Cycloheptanol → Cycloheptyl 4-(methylsulfanyl)butanoate

HRID 280505Notes

Reaction equation

HRID 280505 reaction equation
[CH:1]1([OH:8])[CH2:7][CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[CH3:9][S:10][CH2:11][CH2:12][CH2:13][C:14](O)=[O:15].C[O-].[Na+]>>[CH:1]1([O:8][C:14](=[O:15])[CH2:13][CH2:12][CH2:11][S:10][CH3:9])[CH2:7][CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1

Participants

4

Reactant 3

HCID 10399CycloheptanolHCID 1226044-(Methylsulfanyl)butanoic acidHCID 10942334Sodium Methoxide

Product 1

HCID 13651835Cycloheptyl 4-(methylsulfanyl)butanoate

Procedure

Into a 250 ml reaction flask equipped with magnetic stirrer, heating mantle, thermometer, nitrogen sparger and reflux condenser are placed 11.4 cycloheptanol; 8.1 grams of the ethyl ester of 4-(methylthio)butyric acid and 0.5 grams of a 25% methanolic solution of sodium methoxide.

Workup

  1. customInto a 250 ml reaction flask
  2. customequipped with magnetic stirrer
  3. temperatureheating mantle
  4. temperaturethermometer, nitrogen sparger and reflux condenser

Sources & evidence

ORD record
ord-096b432a929f49338ffcf85cc79180a4
Source dataset
uspto-grants-1986_05
Patent number
US04590082

Reaction notes

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