2-(4-Phenylpiperazinylethyl)nitrobenzene → Benzenamine, 2-(2-(4-phenyl-1-piperazinyl)ethyl)-

HRID 280512Notes

Reaction equation

HRID 280512 reaction equation
[C:1]1([N:7]2[CH2:12][CH2:11][N:10]([CH2:13][CH2:14][C:15]3[CH:20]=[CH:19][CH:18]=[CH:17][C:16]=3[N+:21]([O-])=O)[CH2:9][CH2:8]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1>C(OCC)C>[C:1]1([N:7]2[CH2:8][CH2:9][N:10]([CH2:13][CH2:14][C:15]3[CH:20]=[CH:19][CH:18]=[CH:17][C:16]=3[NH2:21])[CH2:11][CH2:12]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

3

Reactant 1

HCID 132176892-(4-Phenylpiperazinylethyl)nitrobenzene

Product 1

HCID 3070886Benzenamine, 2-(2-(4-phenyl-1-piperazinyl)ethyl)-

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

The 2-(4-phenylpiperazinylethyl)aniline was isolated by crystallization of the evaporation residue dissolved in a mixture of ethyl ether and petroleum ether. Melting point was 103° C.

Sources & evidence

ORD record
ord-2d2ede47768c410e9209b911a1ea95f3
Source dataset
uspto-grants-1986_05
Patent number
US04590193

Reaction notes

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