[2-(4-Methoxyphenyl)-3-oxo-2,3-dihydro-1H-isoindol-1-yl]acetic acid → HCID 19842229, compound

HRID 280537Notes

Reaction equation

HRID 280537 reaction equation
[O:1]=[C:2]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]([CH2:11][C:12]([OH:14])=O)[N:3]1[C:15]1[CH:20]=[CH:19][C:18]([O:21][CH3:22])=[CH:17][CH:16]=1.O=C1C2C(=CC=CC=2)C(CC(O)=O)N1[C:37]1[CH:42]=[CH:41][C:40](Cl)=[CH:39][N:38]=1>>[CH3:22][O:21][C:18]1[CH:19]=[CH:20][C:15]([N:3]2[CH:4]([CH2:11][C:12]([N:38]3[CH2:39][CH2:40][CH2:41][CH2:42][CH2:37]3)=[O:14])[C:5]3[C:10](=[CH:9][CH:8]=[CH:7][CH:6]=3)[C:2]2=[O:1])=[CH:16][CH:17]=1

Participants

3

Procedure

The above (+) acetic acid ester (B) was worked up in the same manner as (v) to give the following compound:

Workup

  1. customto give the following compound

Sources & evidence

ORD record
ord-d01c5356bced4f329e4e4c959e960cbf
Source dataset
uspto-grants-1986_05
Patent number
US04590189

Reaction notes

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