Propylene Glycol → HCID 56619581, compound

HRID 280550Notes

Reaction equation

HRID 280550 reaction equation
[Cl:1][C:2]1[CH:24]=[CH:23][C:5]([C:6]([C:8]2[CH:9]=[C:10]([CH:20]=[CH:21][N:22]=2)[C:11]([NH:13][C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)=[O:12])=[O:7])=[CH:4][CH:3]=1.[CH2:25]([OH:29])[CH:26](O)[CH3:27]>C(O)CO>[CH2:25]1[O:29][C:11]([NH:13][C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)([C:10]2[CH:20]=[CH:21][N:22]=[C:8]([C:6](=[O:7])[C:5]3[CH:23]=[CH:24][C:2]([Cl:1])=[CH:3][CH:4]=3)[CH:9]=2)[O:12][CH:26]1[CH3:27]

Participants

4

Reactant 2

HCID 1030Propylene GlycolHCID 13562483HCID 13562483, compound

Product 1

HCID 56619581HCID 56619581, compoundYield 80%

Reagents, catalysts & solvents 1

HCID 174Ethylene GlycolSolvent

Procedure

2-(4-Chlorobenzoyl)-isonicotinanilide (11 g) was treated as in Synthesis 16 except that ethylene glycol was replaced by propylene glycol. The titled compound was obtained in an amount of 10.5 g (yield: 80%). m.p. 125°-126° C.

Sources & evidence

ORD record
ord-190a54e45daf439d843f99c0c1432434
Source dataset
uspto-grants-1986_05
Patent number
US04590198

Reaction notes

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