5-(((2-Aminoethyl)thio)methyl)-N,N-dimethyl-2-furanmethanamine → HCID 178486566, compound

Participants

Reaction Steps

A toluene (50 ml) solution of 5,6-dimethoxy-3-ethoxy-1,2-benzoisothiazole-1,1-dioxide (D5) (0.13 g) was heated under reflux with 2-[(5-dimethylaminomethylfuran-2-yl)methylthio]ethylamine (0.2 g) for 18 h. Evaporation of the solvent and purification of the residue by column chromatography on silica gel using 5% methanolic chloroform as eluant afforded the title compound (0.1 g).

Provenance & Evidence