Carbon Dioxide → 86792-71-4

HRID 280592Notes

Reaction equation

HRID 280592 reaction equation
Br[C:2]1[CH:11]=[CH:10][C:5]2[S:6][C:7]([CH3:9])=[CH:8][C:4]=2[CH:3]=1.[C:12](=[O:14])=[O:13]>>[CH3:9][C:7]1[S:6][C:5]2[CH:10]=[CH:11][C:2]([C:12]([OH:14])=[O:13])=[CH:3][C:4]=2[CH:8]=1

Participants

3

Reactant 2

HCID 280Carbon DioxideHCID 136630355-Bromo-2-methyl-1-benzothiophene

Product 1

HCID 1366303686792-71-4

Procedure

Conversion of 5-bromo-2-methylbenzo[b]thiophene to the Grignard reagent followed by reaction with carbon dioxide by the method of Example 3(i) gave 2-methylbenzo[b]thiophene-5-carboxylic acid, m.p. 220°-222°.

Sources & evidence

ORD record
ord-da5a92849d294440a8f44e56e1857232
Source dataset
uspto-grants-1986_05
Patent number
US04590200

Reaction notes

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