HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 2-Methylbenzo[b]thiophene-5-carboxylic acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Methanol | HCID 887 | — |
| Reactant | 86792-71-4 | HCID 13663036 | — |
| Product | 2-Methylbenzo[b]thiophene-5-carboxylic acid methyl ester | HCID 13663037 | — |
Reaction Steps
A solution of 2-methylbenzo[b]thiophene-5-carboxylic acid (17.4 g) in methanol (250 ml) was saturated with hydrogen chloride and then heated under reflux for 30 minutes. The solid which crystallised out on cooling was filtered off and dried to give 2-methylbenzo[b]thiophene-5-carboxylic acid methyl ester (16.7 g), m.p. 97°-98°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04590200 |
| Source dataset | uspto-grants-1986_05 |
| ORD ID | ord-60f6a7c3f90f486e81a98c3f04d62b26 |
| Source note | uspto-grants-1986_05 |