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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 280705Generated: October 25, 2026

3-Anilinopropionitrile → 3-Anilino-2-(5-methoxy-1-methyl-3-indolylmethyl)acrylonitrile

https://huagongshe.com/reaction/280705

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-AnilinopropionitrileHCID 14100—
Reactant5-methoxy-1-methyl-1H-indole-3-carbaldehydeHCID 925973—
Product3-Anilino-2-(5-methoxy-1-methyl-3-indolylmethyl)acrylonitrileHCID 67937073—

Reaction Steps

The title compound was prepared from 5-methoxy-1-methylindole-3-carboxaldehyde (S. Misztal, Dessert. Pharm. Pharmacol., 1972, 24, 509) and 3-anilinopropionitrile by the procedure of Example 4A (71%); the structure was confirmed by 1H-NMR.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04590271
Source datasetuspto-grants-1986_05
ORD IDord-e4a7fa38c261430191bbf993e2ebe593
Source noteuspto-grants-1986_05