反应详情

To a suspension of 1.2 g of 4-amino-2,6-dimethylpyrimidine in 30 ml of dry acetonitrile with stirring was added 2.4 g of 2-methoxycarbonylbenzenesulfonylisocyanate. The mixture was stirred for two hours at ambient temperature, allowed to stand for sixteen hours and the desired product, which had precipitated, was removed by filtration and washed with butyl chloride to yield 2.4 g, m.p. 125°-127°. The product showed absorption peaks by Nuclear Magnetic Resource at 4.0, 2.62 and 2.9 ppm; consistent for the product.

1. stirringThe mixture was stirred for two hours at ambient temperature
2. waitto stand for sixteen hours
3. customthe desired product, which had precipitated
4. customwas removed by filtration
5. washwashed with butyl chloride
6. customto yield 2.4 g, m.p. 125°-127°
7. customabsorption peaks by Nuclear Magnetic Resource at 4.0, 2.62 and 2.9 ppm