反应详情

2-hydroxy-4-nitrobenzoic acid (25 g) was dissolved in 100 ml of methanol and sulfuric acid (11 ml, density 1.84). The solution was boiled for 24 hrs, whereupon it was poured onto ice water and extracted with chloroform. The chloroform phase was shaken against sodium hydrogen carbonate solution, dried with magnesium sulfate and evaporated. The product was crystallized from methanol. Yield: 21 g.

1. additionwas poured onto ice water
2. extractionextracted with chloroform
3. dry with materialdried with magnesium sulfate
4. customevaporated
5. customThe product was crystallized from methanol