HCID 23319901, compound → HCID 23319964, compound

HRID 280931Notes

Reaction equation

HRID 280931 reaction equation
[O:1]1[C:7]2[CH:8]=[CH:9][CH:10]=[CH:11][C:6]=2[N:5]([CH2:12][C:13]([O:15]CC2C=CC=CC=2)=[O:14])[CH:4]=[CH:3][CH2:2]1>[C].[Pd]>[O:1]1[C:7]2[CH:8]=[CH:9][CH:10]=[CH:11][C:6]=2[N:5]([CH2:12][C:13]([OH:15])=[O:14])[CH:4]=[CH:3][CH2:2]1

Participants

3

Reactant 1

HCID 23319901HCID 23319901, compound

Product 1

HCID 23319964HCID 23319964, compound

Reagents, catalysts & solvents 1

HCID 178418390HCID 178418390, compoundCatalyst

Procedure

Catalytic reduction of benzyl 1,5-benzoxazepine-5-acetate derivative obtained in Examples 27-35 is carried out using 10% palladium-carbon as a catalyst in a manner similar to that described in Example 17 to give 1,5-benzoxazepine-5-acetic acid derivative shown in Table 3.

Sources & evidence

ORD record
ord-e4bf534a950b4563896053b0c706f0f0
Source dataset
uspto-grants-1986_05
Patent number
US04591458

Reaction notes

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