反应详情

A suspension comprising 20.4 grams (0.1 mole) of 2-formyl-3-methylquinoxaline-1,4-dioxide (m.p. of 180°-182° C.) and 9.9 grams (0.1 mole) of cyanoacetylhydrazine in 200 ml of ethanol was stirred for 4 hours at room temperature. The separated product was sucked off and washed with ethanol, so yielding 22.2 grams (78% of theoretical) of crude material. Upon crystallization from dimethylformamide, yellow crystals melting at a temperature within the range of 255°-260° C. were obtained.

1. washwashed with ethanol
2. customso yielding 22.2 grams (78% of theoretical) of crude material
3. customUpon crystallization from dimethylformamide, yellow crystals
4. custommelting at a temperature within the range of 255°-260° C.
5. customwere obtained