Methanol → Tert-butyl 2-[[5-amino-2-(trifluoromethyl)phenoxy]methyl]pyrrolidine-1-carboxylate

HRID 281125Notes

Reaction equation

HRID 281125 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH:9]([CH2:13][O:14][c:15]2[c:16]([C:24]([F:25])([F:26])[F:27])[cH:17][cH:18][c:19]([N+:21]([O-:22])=[O:23])[cH:20]2)[CH2:10][CH2:11][CH2:12]1.[CH3:28][OH:29].[O:30]1[CH2:31][CH2:32][O:33][CH2:34][CH2:35]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH:9]([CH2:13][O:14][c:15]2[c:16]([C:24]([F:25])([F:26])[F:27])[cH:17][cH:18][c:19]([NH2:21])[cH:20]2)[CH2:10][CH2:11][CH2:12]1

Participants

4

Reactant 3

HCID 887MethanolHCID 312751,4-DioxaneHCID 69018190HCID 69018190, compound

Product 1

HCID 69019989Tert-butyl 2-[[5-amino-2-(trifluoromethyl)phenoxy]methyl]pyrrolidine-1-carboxylate

Sources & evidence

ORD record
ord-28f0ab4c801a436880f972d172dbb926
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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