Pyridine → 6-(2-Ethylaminophenyl)-5,6,7,8-tetrahydronaphthalen-2-ol

HRID 281324Notes

Reaction equation

HRID 281324 reaction equation
[CH3:1][O:2][c:3]1[cH:4][c:5]2[c:6]([cH:7][cH:8]1)[CH2:9][CH:10]([c:11]1[cH:12][cH:13][cH:14][cH:15][c:16]1[NH2:17])[CH2:18][CH2:19]2.[CH3:20][C:21]([O:22][C:23](=[O:24])[CH3:25])=[O:26].[OH:27][c:28]1[cH:29][c:30]2[c:35]([cH:36][cH:37]1)[CH2:34][CH:33]([c:38]1[c:39]([NH:44][C:45]([CH3:46])=[O:47])[cH:40][cH:41][cH:42][cH:43]1)[CH2:32][CH2:31]2.[cH:48]1[cH:49][cH:50][n:51][cH:52][cH:53]1>>[OH:27][c:28]1[cH:29][c:30]2[c:35]([cH:36][cH:37]1)[CH2:34][CH:33]([c:38]1[c:39]([NH:44][CH2:45][CH3:46])[cH:40][cH:41][cH:42][cH:43]1)[CH2:32][CH2:31]2

Participants

5

Reactant 4

HCID 1049PyridineHCID 7918Acetic AnhydrideHCID 230875022-(6-Methoxy-1,2,3,4-tetrahydronaphthalen-2-yl)phenylamineHCID 66626221N-[2-(6-hydroxy-1,2,3,4-tetrahydronaphthalen-2-yl)phenyl]acetamide

Product 1

HCID 230874696-(2-Ethylaminophenyl)-5,6,7,8-tetrahydronaphthalen-2-ol

Sources & evidence

ORD record
ord-8e599d47e77a4a0ebdf04875b7fd1668
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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