o-Fluorobenzaldehyde → 2-[3-[[2-(4-Chlorophenyl)-4-methylthiazol-5-yl]methoxymethyl]piperidin-1-yl]benzaldehyde

HRID 281344Notes

Reaction equation

HRID 281344 reaction equation
[Cl:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[s:9][c:10]([CH2:14][O:15][CH2:16][CH:17]3[CH2:18][NH:19][CH2:20][CH2:21][CH2:22]3)[c:11]([CH3:13])[n:12]2)[cH:6][cH:7]1.[F:23][c:24]1[c:25]([CH:26]=[O:27])[cH:28][cH:29][cH:30][cH:31]1>>[Cl:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[s:9][c:10]([CH2:14][O:15][CH2:16][CH:17]3[CH2:18][N:19]([c:24]4[c:25]([CH:26]=[O:27])[cH:28][cH:29][cH:30][cH:31]4)[CH2:20][CH2:21][CH2:22]3)[c:11]([CH3:13])[n:12]2)[cH:6][cH:7]1

Participants

3

Reactant 2

HCID 67970o-FluorobenzaldehydeHCID 575722153-[[2-(4-Chlorophenyl)-4-methylthiazol-5-yl]methoxymethyl]piperidine

Product 1

HCID 575722032-[3-[[2-(4-Chlorophenyl)-4-methylthiazol-5-yl]methoxymethyl]piperidin-1-yl]benzaldehyde

Sources & evidence

ORD record
ord-8cefa89af74f472ab4644215c10f3ff3
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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