4-(4-Methylpiperazine-1-carbonyl)phenylboronic acid pinacol ester → {4-[1-(2-Chloro-3,6-difluorobenzyl)-1,2,3,4-tetrahydropyrido[2,3-b]pyrazin-7-yl]phenyl}-(4-methylpiperazin-1-yl)methanone
Reaction equation
[CH3:22][N:23]1[CH2:24][CH2:25][N:26]([C:29](=[O:30])[c:31]2[cH:32][cH:33][c:34]([B:37]3[O:38][C:39]([CH3:40])([CH3:41])[C:42]([CH3:43])([CH3:44])[O:45]3)[cH:35][cH:36]2)[CH2:27][CH2:28]1.[Cl:1][c:2]1[c:3]([CH2:4][N:5]2[c:6]3[c:7]([n:11][cH:12][c:13]([I:15])[cH:14]3)[NH:8][CH2:9][CH2:10]2)[c:16]([F:21])[cH:17][cH:18][c:19]1[F:20]>>[Cl:1][c:2]1[c:3]([CH2:4][N:5]2[c:6]3[c:7]([n:11][cH:12][c:13](-[c:34]4[cH:33][cH:32][c:31]([C:29]([N:26]5[CH2:25][CH2:24][N:23]([CH3:22])[CH2:28][CH2:27]5)=[O:30])[cH:36][cH:35]4)[cH:14]3)[NH:8][CH2:9][CH2:10]2)[c:16]([F:21])[cH:17][cH:18][c:19]1[F:20]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-a3f5667c471d440f9631fe4963921134
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
Loading…