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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 281407Generated: October 31, 2026

Tetrahydrofuran → 2,2,2-Trifluoro-N-{2-fluoro-5-[(trimethylsilyl)ethynyl]phenyl}acetamide

https://huagongshe.com/reaction/281407

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantTriphenylphosphineHCID 11776—
ReactantPalladium ChlorideHCID 24290—
ReactantCopper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 24350—
ReactantTrimethylsilylacetyleneHCID 66111—
ReactantN-(5-bromo-2-fluorophenyl)-2,2,2-trifluoroacetamideHCID 59511409—
Product2,2,2-Trifluoro-N-{2-fluoro-5-[(trimethylsilyl)ethynyl]phenyl}acetamideHCID 59511383—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (8/10)
ORD IDord-00f6938e5d2d44a4a386043b57b2379f
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (8/10)