2-((4-((2-(1-Methylethoxy)ethoxy)methyl)phenoxy)methyl)oxirane → 6-[4-[2-[3-(4-(2-Isopropoxyethoxy-methyl)phenoxy)-2-hydroxypropylamino]ethoxy]-3-chloro-phenyl]-4,5-dihydro-3(2H)-pyridazinone

HRID 281957Notes

Reaction equation

HRID 281957 reaction equation
[CH:1]([CH3:2])([CH3:3])[O:4][CH2:5][CH2:6][O:7][CH2:8][c:9]1[cH:10][cH:11][c:12]([O:13][CH2:14][CH:15]2[CH2:16][O:17]2)[cH:18][cH:19]1.[NH2:20][CH2:21][CH2:22][O:23][c:24]1[c:25]([Cl:37])[cH:26][c:27]([C:30]2=[N:35][NH:34][C:33](=[O:36])[CH2:32][CH2:31]2)[cH:28][cH:29]1>>[CH:1]([CH3:2])([CH3:3])[O:4][CH2:5][CH2:6][O:7][CH2:8][c:9]1[cH:10][cH:11][c:12]([O:13][CH2:14][CH:15]([CH2:16][NH:20][CH2:21][CH2:22][O:23][c:24]2[c:25]([Cl:37])[cH:26][c:27]([C:30]3=[N:35][NH:34][C:33](=[O:36])[CH2:32][CH2:31]3)[cH:28][cH:29]2)[OH:17])[cH:18][cH:19]1

Participants

3

Reactant 2

HCID 151078092-((4-((2-(1-Methylethoxy)ethoxy)methyl)phenoxy)methyl)oxiraneHCID 151078226-[4-(2-aminoethoxy)-3-chloro-phenyl]-4,5-dihydro-3(2H)-pyridazinone

Product 1

HCID 148844256-[4-[2-[3-(4-(2-Isopropoxyethoxy-methyl)phenoxy)-2-hydroxypropylamino]ethoxy]-3-chloro-phenyl]-4,5-dihydro-3(2H)-pyridazinone

Sources & evidence

ORD record
ord-682efd82e49b467eac5ca9cbd3433308
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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